Complication of Mechanical Ventilation

Complication of Mechanical Ventilation

David Ray Velez, MD

Intubation/Endotracheal Tube Complications

  • Local Trauma
  • Endotracheal Tube Obstruction or Occlusion
  • Esophageal Intubation
  • Right- or Left-Mainstem Bronchus Intubation
  • Aspiration
  • Tracheal Stenosis or Necrosis

Patient-Ventilator Dyssychrony

Ventilator-Induced Lung Injury (VILI)

  • Atelectrauma – Trauma from the Shear-Stress Created by Recruiting/Opening Atelectatic Alveoli
  • Barotrauma – Trauma from High Inspiratory Pressure Causing Alveolar Over-Distention
  • Volutrauma – Trauma from Increased Volume Causing Alveolar Over-Distention
  • Biotrauma – Additional Injury Due to the Inflammatory Response to Mechanical Injury
  • *See Ventilator-Induced Lung Injury (VILI)

Dynamic Hyperinflation (DHI)

  • Definitions:
    • Air Trapping (Air Stacking): Hyperinflation (Increased End-Expiratory Lung Volumes) Due to Incomplete Exhalation
    • Auto PEEP (Intrinsic PEEP/PEEPi): Increased Positive End Expiratory Pressure from Hyperinflation
  • *See Dynamic Hyperinflation (DHI)

Ventilator-Induced Diaphragmatic Dysfunction (VIDD)

  • Diaphragm Muscle Atrophy and Contractile Dysfunction
  • Caused by Oxidative Stress, Protein Imbalance, and Myotrauma

Ventilator-Associated Pneumonia (VAP)

  • *See Ventilator-Associated Pneumonia (VAP)

Other Complications

  • Secretion Retention
  • Gastritis and Peptic Ulcer
  • Oxygen Toxicity
  • Increased Intrathoracic Pressure Causing Decreased Venous Return and Cardiac Output